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Lori Loughlin was out on the town with actor James Tupper the night before her separation from Mossimo Giannulli became public.

The "Full House" star and James -- who was previously married to the late actress Anne Heche -- were photographed leaving The Bird Streets Club in West Hollywood on Wednesday night after grabbing dinner together. Backgrid

James was seen comforting Lori, who appeared upset, as the pair chatted and laughed while slipping out of the exclusive hot spot on the Sunset Strip.

The sighting came just hours before Lori's rep confirmed on Thursday that she and Mossimo are officially separated after 28 years of marriage. Getty

But before you jump to conclusions ... sources with direct knowledge tell TMZ Lori a

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