Should I start Tyjae Spears, Sean Tucker, Kendre Miller for Week 5? Fantasy football start 'em, sit 'em picks and recommendations for the 2025 NFL season.

Probably the most fun thing of all time to do in any line of work is try to predict which backup running backs will have big games when they get more work due to injuries to the RBs ahead of them on their depth charts.

I was joking -- it's actually very difficult. There are some ways we can at least frame their range of outcomes to be more certain of how they might produce in their next game, though.

With Tennessee Titans running back Tyjae Spears returning from injury, Buccaneers RB Bucky Irving (foot) being out with injury, and Saints RB Alvin Kamara potentially losing work to his backup, the running back landscape is interest

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