The New England Patriots (2-2) and the Buffalo Bills (4-0) meet for Sunday Night Football at Highmark Stadium in Orchard Park, New York. Kickoff is scheduled for 8:20 p.m. ET (NBC). Let's analyze BetMGM Sportsbook's Patriots vs. Bills odds and tab the 5 best prop bets to win among SportsbookWire's expert NFL picks and predictions for Week 5.

The Patriots enter play with momentum after throttling the Carolina Panthers 42-13 at home last Sunday, easily covering as 5.5-point favorites as the Over (41.5) cashed. New England is also 1-0 straight up (SU) and against the spread (ATS) against the AFC East Division.

Patriots QB Drake Maye completed 14-of-17 passes for 203 yards, 2 TDs and 0 INTs with a rushing score against the Panthers, while both rookie RB TreVeyon Hend

See Full Page