The New England Patriots will face the Buffalo Bills in Week 5 of the NFL season on Sunday at Highmark Stadium.

How to Watch Patriots vs Bills

When: Sunday, October 5, 2025

Time: 8:20 PM ET

TV Channel: NBC

Live Stream: Fubo ( try for free )

The New England Patriots (2–2) arrive in Buffalo riding the momentum of their 42–13 win over the Panthers. Second‑year quarterback Drake Maye has shown promise, especially in recent weeks, and New England's run game, led by Rhamondre Stevenson and TreVeyon Henderson, could try to exploit Buffalo's weaker run defense. If they can take some pressure off Maye by running the ball effectively, it will give the Patriots the best chance to hang around in this one.

The Buffalo Bills (4–0) remain a dominant force, boasting the league's second‑best o

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