Stockholm, Oct 6: Mary E Brunkow, Fred Ramsdell and Shimon Sakaguchi won the Nobel Prize in medicine on Monday for their discoveries concerning peripheral immune tolerance.

The award is the first of the 2025 Nobel Prize announcements and was announced by a panel at the Karolinska Institute in Stockholm.

Peripheral immune tolerance is one way the body helps keep the immune system from getting out of whack and attacking your own tissues instead of foreign invaders.

"The Nobel Prize laureates identified the immune system’s security guards, regulatory T cells, thus laying the foundation for a new field of research. The discoveries have also led to the development of potential medical treatments that are now being evaluated in clinical trials," read the official website of the coveted award

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