Nobel Prize Awarded For Basic Research Into Immune Tolerance

The 2025 Nobel Prize in Physiology or Medicine was awarded for research into the mechanism of immune tolerance. (AP Photo/Jacquelyn Martin, File) Copyright 2020 Jacquelyn Martin. All rights reserved.

The Nobel Prize in Physiology or Medicine was awarded on Monday to three researchers who furthered our knowledge of immune system regulation. They made, “discoveries concerning peripheral immune tolerance,” according to the Nobel Prize committee . In other words, their work has helped explain how our body differentiates self from non-self and good from bad. These advancements could have profound impacts on myriad aspects of human health, from cancer to autoimmune diseases to chronic viral infections.

The laureates are Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi. Brunkow was aw