Jacksonville Jaguars quarterback Trevor Lawrence (16) is celebrated by offensive tackle Patrick Mekari (65) and tight end Hunter Long (84) for his touchdown score with other teammates joining in for his game-winning touchdown during the fourth quarter of an NFL football matchup at EverBank Stadium, Monday, Oct. 6, 2025, in Jacksonville, Fla. The Jacksonville Jaguars edged the Kansas City Chiefs 31-28. [Corey Perrine/Florida Times-Union]

The Jacksonville Jaguars earned a signature win on Trevor Lawrence's 26th birthday. The Jaguars quarterback led a rally from a 14-point deficit to defeat the Kansas City Chiefs, 31-28.

The win improved the Jaguars to 4-1, but it’s easily the biggest victory of first-year coach Liam Coen.

The Chiefs had a 14-7 lead at halftime, but the Jaguars tied the ball game in the third quarter. Momentum swung Jacksonville’s way when linebacker Devin Lloyd notched a huge 99-yard pick-six to give the Jaguars a 21-14 advantage.

Kansas City was able to reclaim the lead, but then Lawrence led the Jaguars for a go-ahead score late in the fourth quarter to lift the team to a huge victory.

Patrick Mahomes threw for 318 yards, one touchdown and one interception in the loss. The Chiefs quarterback also led Kansas City with 60 yards on the ground.

USA TODAY Sports examines the winners and losers from the final game of Week 5:

Winners

Devin Lloyd shines

Lloyd is already having himself an October, fresh off winning the AFC Defensive Player of the Month.

Lloyd had a 99-yard pick-six on Patrick Mahomes during the third quarter that gave Jacksonville a 21-14 lead. Lloyd read Mahomes’ eyes and stepped in front of the intended receiver, JuJu Smith-Schuster.

It was the longest pick-six in Jaguars history.

The Jaguars linebacker produced 17 tackles, three interceptions, two tackles for loss and a fumble recovery in September.

Lloyd now has an NFL-high four interceptions. He’s an early candidate for NFL Defensive Player of the Year.

Trevor Lawrence tastes victory on his birthday

Lawrence earned Monday’s win.

The Jaguars quarterback had a costly fumble at the goal line in the first quarter, but he responded after the early mishap.

Lawrence threw a couple of nice passes during Jacksonville’s game-winning seven-play, 60-yard touchdown drive, including a 33-yard dime to WR Brian Thomas Jr. that put the team in scoring position.

A few plays later, Lawrence capped off the drive on an improbable one-yard touchdown run. Lawrence tripped during the play, got up and managed to find the end zone.

To put the icing on the cake (literally), the game-winning touchdown came on Lawrence’s birthday.

The quarterback completed 18-of-25 passes for 221 yards, one touchdown and one interception. He had two rushing touchdowns in the win.

Travis Hunter

Rookie Travis Hunter had a couple of electrifying plays on offense.

The two-way star had an acrobatic 44-yard catch in the third quarter. The play was key during Jacksonville’s game-tying touchdown drive.

Hunter compiled three catches for 64 yards. He had two tackles and one pass defensed on defense.

Losers from Jaguars vs Chiefs

Game officials

Trevor Lawrence’s lone interception wasn’t on him. Game officials missed a blatant pass interference on Chiefs safety Jaden Hicks.

Hicks knocked Jaguars WR Parker Washington down on what appeared to be a crossing route. Lawrence threw the football in anticipation of Washington being at a specific spot, but Chiefs cornerback Trent McDuffie was there for an easy interception.

The missed call ended Jacksonville’s momentum. The Chiefs scored a touchdown two plays later to tie the game at 21 apiece.

Chiefs penalties

The Chiefs were flagged a season-high 13 times for a total of 109 yards. And the squad should've been flagged 14 times because the referees missed an obvious pass interference.

Follow USA TODAY Sports' Tyler Dragon on X @TheTylerDragon.

This article originally appeared on USA TODAY: A Defensive Player of the Year candidate and a rookie among Jaguars-Chiefs winners, losers

Reporting by Tyler Dragon, USA TODAY / USA TODAY

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