New Delhi: People with severe obesity are likely to have their lungs age faster, according to a study.
Researchers from the University of Bonn in Germany investigated how the lungs adapt to nutritional challenges in obesity.
The team showed that obesity remodels the extracellular matrix in the lungs -- the protein-based "scaffolding" that gives the lungs their shape and stability.
“These changes in lung tissue are similar to those that normally occur with age and suggest that being overweight causes the lungs to ‘age’ prematurely,” they said in the paper published in the journal Cell Reports.
The team used state-of-the-art multi-omics approaches to simultaneously examine proteins, fats, and genes for specific questions. They combined this analysis with microscopic image analyses and