A new study published in the journal of Allergologia et immunopathologia showed that although there was no discernible improvement over isotonic saline, 3% hypertonic saline nasal irrigation decreased nasal symptoms and antihistamine usage in individuals with allergic rhinitis.

There is ongoing discussion on the relative effectiveness of 0.9% isotonic saline and 3% hypertonic saline nasal irrigation (HSNI). Thus, this study evaluated the effectiveness of HSNI as a therapeutic strategy for both adults and children with AR.

From the beginning until May 8, 2024, a comprehensive search of Scopus, PubMed, and Cochrane Central was conducted to find randomized controlled trials (RCTs) that compared 3% HSNI with control. Antihistamine usage and overall nasal symptom ratings were the main outco

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