Fantasy football rankings - updated defense (DST) Week 6 rankings for 2025. Read the top-accuracy fantasy football DEF rankings for NFL team defenses.

Through the first five weeks of the fantasy football season, we have seen several spike weeks carry fantasy managers to wins. It's important to find a high-upside D/ST each week, so use updated Week 6 fantasy football defense (DST) rankings for 2025 to pinpoint the best team defense for your lineups. In the rankings below, you will see where the Green Bay Packers, Los Angeles Rams, Seattle Seahawks, New England Patriots, Las Vegas Raiders, and Buffalo Bills defenses stand, among all other D/STs.

Our defense fantasy football rankings for Week 6 are put together by Nick Mariano . Below the rankings, you will also find key fantasy footb

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