The San Francisco 49ers will face the Tampa Bay Buccaneers in Week 6 of the NFL season on Sunday at Raymond James Stadium.

How to Watch 49ers vs Buccaneers

When: Sunday, October 12, 2025

Time: 4:25 PM ET

TV Channel: CBS

Live Stream: Fubo ( try for free )

The 49ers have had to rely far too much on Christian McCaffrey so far this season, which has led to inefficiencies on the ground as teams key in on the star running back. San Francisco will get healthier as the season continues, but for now, they are still without most of their key playmakers on offense. It will be the McCaffrey show once again, as the 49ers look to improve their record to 5-1 on the year.

Tampa Bay may have found the steal of the draft in Emeka Egbuka, as the first-year wide receiver already looks like a star

See Full Page