Tamil Nadu government has revoked the manufacturing licence of Sresan Pharmaceuticals, the company responsible for producing the adulterated cough syrup Coldrif, which has been linked to the deaths of at least 23 children in Madhya Pradesh. The state government announced the shutdown of the company on Monday, following an inspection by the Drug Control Department.

During the inspection, officials discovered that Coldrif contained 48.6 per cent of Diethylene Glycol (DEG), a toxic substance. The company was also found to have significant deficiencies in its manufacturing practices, with over 300 critical and major violations of Good Manufacturing Practices (GMP) and Good Laboratory Practices (GLP).

G Ranganathan, the owner of Sresan Pharmaceuticals, has been arrested by a special investigation team from Madhya Pradesh. Additionally, the Enforcement Directorate conducted raids at the company's premises and targeted some officials in connection with a Prevention of Money Laundering Act (PMLA) case.

The Tamil Nadu government stated, "The drug manufacturing license of Sresan Pharmaceuticals has been completely cancelled, and the company has been closed. Orders have been given to conduct a detailed inspection of other drug manufacturing companies located in Tamil Nadu."

As a precaution, the sale of Coldrif has been prohibited across the state since October 1. The Drug Testing Laboratory in Chennai has declared the syrup "Not of Standard Quality." In response to the tragic incidents in Madhya Pradesh and Rajasthan, both state and central governments are intensifying efforts to crack down on contaminated drugs, including cough syrups and antibiotics.