The Smithsonian Institution, the world’s largest museum and research complex, has shuttered its museums and the National Zoo as the federal government shutdown drags into its third week, leaving tourists and Washington residents locked out of some of the nation’s most treasured cultural landmarks.

The Smithsonian had remained open for nearly two weeks after the Oct. 1 shutdown by relying on leftover funds from prior years, but with those reserves depleted, all 21 museums in Washington, D.C., and New York, along with 14 research centers and the National Zoo, have now closed their doors.

Visitors to the National Mall have encountered locked entrances and printed notices announcing the closures.

“You won’t get to see the animals today,” said Mario de la Fuente, who had brought his 2-year-o

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