Delaware Blue Hens quarterback Nick Minicucci (4) winds up for a pass against Western Kentucky during Delaware's first home CUSA football game, which was nationally televised, at Delaware Stadium in Newark on Oct. 3, 2025. Western Kentucky won 27-24.

Conference USA is providing a treat to college football fans on Wednesday night when two teams, each vying for a postseason bowl bid, square off on national television to get some national recognition.

The Delaware Blue Hens (3-2, 1-1 CUSA), in their first year in Division I FBS, get a shot at the Jacksonville State Gamecocks (3-3, 2-0 CUSA) from AmFirst Stadium in Jacksonville, Alabama. Both of these teams have the chance to get to four wins on the year and inch closer to the goal of a bowl bid.

If you are looking for some betting advice for the matchup, we've got you covered. Here are the latest odds for the game, courtesy of BetMGM.

Stream Delaware vs. Jacksonville State

Delaware vs. Jacksonville State game odds

All college football odds via BetMGM

  • Spread: Delaware - 2.5 (-110), Jacksonville State +2.5 (-110)
  • Money Line: Delaware -145, Jacksonville State +120
  • Over-Under: Over 57.5 (-110), Under 57.5 (-110)

Delaware vs. Jacksonville State prediction, pick:

What a fun little game the CUSA is giving us on this fine Wednesday night. Two teams that have shown an ability to win meet up with a chance to make a statement in the conference.

Delaware, new to the conference, nearly stunned Western Kentucky last week, the cream of the crop in the conference. Jacksonville State survived a scare from Sam Houston. Nonetheless, this one should be competitive.

Delaware has the clean advantage in the quarterback department in this game with Nick Minicucci (1,379 yards, 64.5% completion, 8 TD) manning the offense. Jacksonville State has played a few QBs who have mustered up 851 yards with three touchdowns to four interceptions. What they do have is the nation's leading rusher in Cam Cook with 832 yards and seven touchdowns.

Minicucci went for 314 passing yards last week and found four different targets with at least four catches, and Jacksonville State is No. 58 in the country in passing yards allowed. The problem for Delaware?

They allowed 154.6 rushing yards per game at 4.5 yards per carry. Cam Cook gets loose just enough to give the Gamecocks the home win.

Prediction: Jacksonville State 28, Delaware 27

Best Bet: Jacksonville State +2.5

Delaware vs. Jacksonville State channel, start time, streaming:

Time: 7 p.m. ET

TV Channel: ESPN

Live Stream: ESPN App

Get more betting analysis and predictions at Sportsbook Wire.

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This article originally appeared on College Sports Wire: Delaware vs. Jacksonville State: Week 8 College Football Betting Odds, Prediction

Reporting by Riley Donald, College Sports Wire / College Sports Wire

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