Microdosing GLP-1 weight loss drugs like semaglutide is trendy, with supporters touting benefits such as lower costs and potentially fewer side effects. But some doctors are skeptical, calling it “experimental.”

The practice has gotten celebrity endorsement.

Bravo TV host Andy Cohen says he lost “a good chunk of weight” by microdosing a GLP-1 drug all summer, though he didn’t say which one or offer details of his regimen.

“It kickstarted something,” he told TODAY in September.

Actor Rebel Wilson told USA Today that microdosing helps stabilize her weight after she lost more than 80 pounds in 2020 by working out and eating a high-protein diet. To keep that progress, she says she sometimes takes an unspecified GLP-1 medication.

“I had a very good response to it because it meant I cou

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