One too many bottles of red wine will leave most humans with a throbbing skull the following morning. However, a few unfortunate souls will develop a nasty headache after just consuming a small tipple of red wine, while other alcoholic beverages leave them feeling fine (if not pleasantly numbed). The rest of this article is behind a paywall. Please sign in or subscribe to access the full content.

There are a few ideas as to what causes the notorious “red wine headache”. A leading theory is that some people lack the enzymes to break down the high concentrations of chemicals commonly found in the grape, especially their skin.

Red wine is fermented with the grape skins on, unlike white wine, which is made after the skins are removed. This leaves red wine with higher levels of compounds f

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