Teams contending for their respective division leads meet when the Los Angeles Rams face the Jacksonville Jaguars in London, England, on Sunday morning. Los Angeles is coming off a 17-3 win at Baltimore, while Jacksonville dropped a 20-12 decision to Seattle this past week. The Rams (4-2), who are tied for the NFC West lead, are 2-1 on the road this season. The Jaguars (4-2), who are second and one game behind the Indianapolis Colts in the AFC South, are 3-1 as the home team in 2025. Los Angeles wide receiver Puka Nacua (ankle) has been ruled out.

Kickoff from Wembley Stadium is set for 9:30 a.m. ET. The Rams lead the all-time series 5-1, including wins in each of the last three meetings. The Rams are 3-point favorite in the latest Jaguars vs. Rams odds, while the over/under for tot

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