When it comes to Lori Loughlin 's ex, John Stamos has no mercy.

The Full House star expressed his whole-hearted support for his longtime onscreen wife following her separation from husband of 27 years Mossimo Giannulli , and didn’t hold back sharing his unfiltered thoughts about the designer.

"I will never talk to him again," Stamos told Josh Peck and Ben Soffer on the Oct. 20 episode of their Good Guys podcast. "He's a terrible narcissist."

"Whatever he did to her, it busted her up to the core. And she put up with a lot over the years for this guy," he continued. "I know a lot, and I was by her side through a lot of it."

The ER alum emphasized how heartbroken he is for his friend of 40 years.

"I know she's just devastated," Stamos—who also starred with Lough

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