A new study published in the journal of Nature Scientific Reports found that “matching transformation system” (MA-T) has a strong disinfection ability and superior biocompatibility, suggesting it could serve as a promising alternative to traditional irrigants like sodium hypochlorite (NaOCl).

Apical periodontitis arises primarily from bacterial invasion and biofilm formation inside the root canal system. Conventional treatment relies heavily on mechanical cleaning combined with chemical irrigation. However, widely used agents such as NaOCl can damage periapical tissues and exhibit cytotoxic effects on surrounding cells. MA-T, a recently developed chlorine dioxide-based solution, has now been evaluated for its antibacterial performance and cytocompatibility.

The study examined MA-T’s an

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