Minnesota Vikings running back Jordan Mason (27) warms up before the game against the Philadelphia Eagles at U.S. Bank Stadium in Minneapolis on Oct. 19, 2025.

The Los Angeles Chargers and Minnesota Vikings are squaring off in a Week 8 "Thursday Night Football" during which both squads will be desperate to get a win.

The Chargers (4-3) have dropped three of their last four games after a 3-0 start to the season. They have fallen behind the Denver Broncos in the AFC West race while the Kansas City Chiefs have steadily gained on them amid a hot streak from Patrick Mahomes.

Meanwhile, the Vikings (3-3) are sitting in the cellar of a loaded NFC North. They have alternated wins and losses while navigating uncertainty at quarterback, but could use a victory to catapult them back into the division and NFC wild-card races.

The Chargers and Vikings are both dealing with injury question marks in their backfields, so that could create opportunities for some fun bets on high-volume runners. Any rushing struggles could also convince either team to take a pass-happy approach, which would create different types of opportunities for bettors.

What are the best bets for "Thursday Night Football" in Week 8? Here's a look at some prop bets and anytime TD wagers to consider as the Chargers and Vikings square off in what profiles as a closely contested "TNF" battle.

Thursday Night Football best bets

All odds are via BetMGM as of Thursday.

Kimani Vidal UNDER 55.5 rushing yards (-105)

Vidal should handle most of the rushing workload for the Chargers with Hassan Haskins (hamstring) sidelined. As such, many will be looking to back Vidal as a high-volume runner against a middle-of-the-pack Vikings run defense allowing 117.7 rushing yards per game.

That said, it's worth noting linebacker Blake Cashman returned to action for the Vikings last week. As a result, the team was able to limit the Eagles to 45 total rushing yards, including just 44 for Saquon Barkley.

Minnesota has allowed an average of 82 rushing yards per game in Cashman's two games this season, and 54 rushing yards per game to running backs. His presence may make it more difficult for Vidal – who is averaging just 2.9 yards per carry excluding his breakout game against the Miami Dolphins – to find consistent room between the tackles.

Jordan Mason OVER 55.5 rushing yards (-115)

Even if Aaron Jones is able to return from a hamstring injury in Week 8, Mason figures to get enough work to go over his rushing total. The Chargers have allowed at least 118 rushing yards in five consecutive games, and Mason will likely continue to be the Vikings' top between-the-tackles option until Jones is back up to full game speed.

Mason has averaged 55.3 rushing yards per game over his last three contests despite playing behind a banged up offensive line. He should find far more success playing a Chargers defense that ranks 31st league-wide in defensive EPA per rushing attempt, ahead of only the Baltimore Ravens.

Carson Wentz OVER 0.5 interceptions thrown (-135)

Wentz has been solid across four starts for the Vikings, but interception issues continue to follow him. He has averaged an interception per game across his four starts while holding a 3.4% turnover-worthy play rate, ranked 18th in the NFL among 41 quarterbacks.

The Chargers are tied for eighth in the NFL with six interceptions on the season. Derwin James and Co. should find a way to force Wentz into another mistake, especially if they can build a lead against Minnesota and force the Vikings into a pass-heavy game plan.

Jordan Addison anytime TD scorer (+200)

You can make the case for either Jordan as a good TD scorer bet, as Mason's odds currently sit at +115. That said, Addison's 2-to-1 odds represent a good value, as he has established himself as one of Wentz's favorite targets since his return to the lineup in Week 4.

Since Week 4, Addison has been targeted 26 times, good for second-most on the team behind only Justin Jefferson (32). That includes six targets in the red-zone, which matches Jefferson's total for the entire season.

If the Chargers continue the defensive trend of paying more attention to Jefferson than Addison, that could allow the third-year receiver to find more open space near the end-zone. That would make him a threat to score his second touchdown of the season.

This article originally appeared on USA TODAY: Chargers vs. Vikings best bets, top NFL player props, anytime TD scorers for TNF

Reporting by Jacob Camenker, USA TODAY / USA TODAY

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