The New York Knicks (1-0) have the Boston Celtics (0-1) rolling into town for an Eastern Conference showdown on Friday night. The Knicks opened the campaign with a 119-111 win over the Cleveland Cavaliers on Wednesday night. The Celtics weren't able to defend their home court, as the Philadelphia 76ers beat Boston 117-116 on Oct. 22. The Celtics swept the season series 4-0 during the 2024-25 season.

Tipoff is at 7:30 p.m. ET from Madison Square Garden in New York City, where the Knicks went 27-14 last season. New York is a 3.5-point favorite in the latest Celtics vs. Knicks odds, while the over/under for total points scored is 229.5. Before locking in any Celtics vs. Knicks picks, make sure to check out the NBA predictions and betting advice from the SportsLine Projection Model .

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