The No. 8 Ole Miss Rebels (6-1) and the No. 13 Oklahoma Sooners (6-1) link up on Saturday afternoon in a critical SEC matchup with both conference and College Football Playoff implications. The Rebels had their six-game win streak halted last weekend in a 43-35 loss at Georgia. Meanwhile, Oklahoma took down South Carolina 26-9.

Kickoff from the Gaylord Family-Oklahoma Memorial Stadium in Norman, Oklahoma, is at noon ET. The Sooners are 5.5-point favorites in the latest Ole Miss vs. Oklahoma odds, while the over/under for total points scored is 52.5 via SportsLine consensus. Before making any Oklahoma vs. Ole Miss picks, check out the college football predictions from the SportsLine Projection Model .

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