SANTA CLARA, Calif. — Quarterback Brock Purdy will miss his fourth straight game and sixth in the past seven weeks for the San Francisco 49ers with a toe injury.

Coach Kyle Shanahan said Friday that Purdy was ruled out this week against the Houston Texans but will travel for the game as his condition has improved. Purdy skipped the past two road trips for San Francisco.

Mac Jones will make his sixth start of the season in place of Purdy. Jones is 4-1 as a starter, triggering a $400,000 incentive bonus for his contract by winning a fourth game. Jones will make an additional $100,000 every time he plays at least 25% of the snaps in a 49ers win. Jones leads the NFL with 280.8 yards passing per game.

The Texans will be without two of their top receivers with Nico Collins ruled out after suf

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