Oct 18, 2025; Nashville, Tennessee, USA; Vanderbilt Commodores quarterback Diego Pavia (2) celebrates the win against the Louisiana State Tigers during the second half at FirstBank Stadium. Mandatory Credit: Steve Roberts-Imagn Images

Week 9 of the 2025 college football season continues Saturday with a big SEC battle between the Vanderbilt Commodores and the Missouri Tigers

The Commodores are coming off their biggest win of the year as they beat LSU at home 31-24 last weekend. The win pushed their record to 6-1 overall and 2-1 in the SEC.

The Tigers were off last week after beating Auburn in double overtime in ther last game. The win helped them avoid a second straight loss and moved them to 6-1 overall and 2-1 in the SEC.

Stream Vanderbilt vs. Missouri

If you're looking to get back in the swing of football season and need some betting advice for Saturday's matchup in Nashville, we've got you covered. Here are the latest odds for the game, courtesy of BetMGM.

Vanderbilt vs Missouri game odds:

All college football odds via BetMGM

  • Spread: Vanderbilt -2.5 (-115), Missouri +2.5 (-105)
  • Money Line: Vanderbilt -145, Missouri +120
  • Over-Under: Over 52.5 (-110), Under 52.5 (-110)

Vanderbilt vs Missouri prediction, pick:

The Commodores have shown they can compete with the top teams in the SEC this year and they get another test on Saturday. Diego Pavia has been great at quarterback for them and will be the difference on Saturday. The Tigers are good, but they aren't going to have enough answers. The Commodores get the close win.

Prediction: Vanderbilt 24, Missouri 20

Best Bet: Vanderbilt -2.5, Under 52.5

Vanderbilt vs Missouri channel, start time, streaming:

Time: 3:30 p.m. ET

TV Channel: ESPN

Live Stream: ESPN App

Get more betting analysis and predictions at Sportsbook Wire.

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This article originally appeared on College Sports Wire: Vanderbilt vs Missouri: Week 9 College Football Betting Odds, Prediction, Pick

Reporting by Adam Childs, College Sports Wire / College Sports Wire

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