Earlier this year, the musical group Jonas Brothers, partnering with Mastercard , released a new single and video dedicated to the fight against cancer. As Stand Up to Cancer ambassadors, Jonas Brothers helped elevate awareness of the cause with “I Can’t Lose,” honoring everyone affected by the disease and celebrating the triumph of beating it.

On Saturday, Jonas Brothers performed “I Can’t Lose” after the fifth inning of Game 2 of the World Series at Rogers Centre in Toronto, adding a special new layer to the long-standing SU2C moment that is a signature of Major League Baseball’s big events.

As has been tradition since 2009, the in-stadium Stand Up to Cancer placard moment, in partnership with Mastercard, aired live on FOX. Players, umpires, managers, coaches and fans held up signs h

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