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The Indianapolis Colts return home after a dominant 38-24 road win in Los Angeles, while the Titans are reeling at 1-6 following a demoralizing loss to the Cardinals.

This is a stark contrast in form: the Colts are first in the AFC South and boast the NFL’s No. 1 scoring offense , while Tennessee ranks dead last offensively.

Jonathan Taylor continues to steamroll defenses, and Daniel Jones is efficiently running one of the league’s most potent passing attacks.

Oddsmakers have the Colts installed as 14.5-point favorites.

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