Saturday’s showdown between Penn State and Ohio State at Ohio Stadium marks one of the most anticipated matchups of the Big Ten season. The Buckeyes enter as heavy 20.5-point favorites and hold a 93% chance to win, according to Dimers’ predictive model , which simulated the game 10,000 times. Ohio State’s offense has surged behind its balanced attack and elite protection up front, while its defense continues to rank among the best in the nation. Penn State, meanwhile, faces the challenge of rebounding after a rocky midseason stretch and will need a near-flawless performance to hang with the Buckeyes on the road.
Kickoff in Columbus is set for noon ET, with the total listed at 44.5 points. Dimers projects a 33–13 Ohio State victory and identifies Under 44.5 (-110) as the best betting

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