Nebraska Cornhuskers running back Emmett Johnson (21) runs the ball for a touchdown against the Southern California Trojans during the first half at the Los Angeles Memorial Coliseum.

The rest of the season is on the line when Southern California visits Nebraska in a do-or-die Week 10 matchup in the Big Ten.

USC is fresh off a bye week, but last time the Trojans were on the field Notre Dame was running wild on them as they lost to their rival in what was a game it needed to win to boost its College Football Playoff hopes.

After a disappointing showing at Minnesota, Nebraska got back on track with hard-fought victory over Northwestern to keep its postseason hopes alive. At 6-2, the Cornhuskers are off to their best start since 2016.

The winner of this game will keep its slim playoff hopes afloat, while the loser can practically kiss those dreams away. Here's how to watch the USC-Nebraska game, including time, TV channel and streaming information, and game odds:

What TV channel is USC vs Nebraska on today?

  • TV: NBC
  • Streaming: Peacock | Fubo (free trial)

USC and Notre Dame will air nationally on NBC in Week 10 of the 2025 college football season from Memorial Stadium in Lincoln, Nebraska. Noah Eagle (play-by-play) and Todd Blackledge (analyst) will call the game from the booth while Kathryn Tappen will serve as the sideline reporter.

Streaming options include Peacock, NBC's subscription streaming service, and Fubo, which carries NBC and offers a free trial.

USC vs Nebraska time today

  • Date: Saturday, Nov. 1
  • Start time: 7:30 p.m. ET

The game between the Trojans and Cornhuskers will kick off at 7:30 p.m. ET on Oct. 18 from Memorial Stadium.

USC vs Nebraska predictions, picks, odds

Odds courtesy of BetMGM as of Wednesday, Oct. 29.

  • Spread: USC (-6.5)
  • Over/under: 59.5
  • Moneyline: USC (-235) ∣ Nebraska (+190)

Prediction: USC 31, Nebraska 24

Nebraska will be pumped with its blackout in full force, but it has a tremendous challenge going against the USC offense. The Trojans tighten up the defense off the bye week and pick up a critical road victory.

This article originally appeared on USA TODAY: Where to watch USC vs Nebraska: Time, TV channel for Week 10 game

Reporting by Jordan Mendoza, USA TODAY / USA TODAY

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