Scientists use nanotechnology to successfully reverse Alzheimer’s symptoms in mice

Scientists have developed an innovative nanotechnology treatment that reverses Alzheimer's disease in mice by restoring the brain’s blood-brain barrier (BBB), a critical vascular checkpoint maintaining brain health . Published in the journal Signal Transduction and Targeted Therapy, the study was led by the Institute for Bioengineering of Catalonia (IBEC) and West China Hospital Sichuan University (WCHSU), in partnership with UK collaborators. Unlike conventional nanomedicines used as drug carriers, these bioactive nanoparticles act directly as “supramolecular drugs,” repairing BBB function and promoting the clearance of toxic waste proteins from the brain.

Alzheimer’s disease is closely linked to vasc

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