A recent cross-sectional study by Pariya Mostafazadeh and colleagues, published in Scientific Reports, found that higher dietary intake of the aromatic amino acids tyrosine and phenylalanine is associated with increased severity of Pemphigus vulgaris (PV). The researchers assessed 138 patients with confirmed PV using a 168-item food frequency questionnaire to estimate consumption levels of tyrosine, phenylalanine and tryptophan. After adjusting for age, sex, disease duration, corticosteroid use, protein intake, body mass index and total energy intake, they observed that individuals in the highest quartile of tyrosine consumption had significantly greater disease severity compared with those in the lowest quartile. Additionally, phenylalanine intake showed a positive linear association with
High Tyrosine and Phenylalanine Intake Linked to Greater Severity of Pemphigus vulgaris: Study
Medical Dialogues4 hrs ago
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