LOUISVILLE, Ky. - At least seven people are dead and 11 injured in a UPS cargo plane crash that happened Tuesday afternoon shortly after taking off from Louisville Muhammad Ali International Airport.

The incident prompted a large emergency response and a shelter-in-place order across parts of the city.

What they're saying:

UPS’s largest package handling facility is in Louisville. The hub employs thousands of workers, has 300 daily flights and sorts more than 400,000 packages an hour.

"UPS has been notified of an incident/accident involving one of our aircraft in Louisville, KY," the company said on social media shortly after the incident.

The Federal Aviation Administration released a statement:

UPS Flight 2976 crashed around 5:15 p.m. local time on Tuesday, Nov. 4, after departing

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