The Brief

LOUISVILLE, Ky. - A UPS cargo plane crashed Tuesday afternoon shortly after taking off from Louisville Muhammad Ali International Airport, prompting a large emergency response and a shelter-in-place order across parts of the city.

What they're saying:

"UPS has been notified of an incident/accident involving one of our aircraft in Louisville, KY," the company said on social media shortly after the incident.

The Federal Aviation Administration released a statement:

UPS Flight 2976 crashed around 5:15 p.m. local time on Tuesday, Nov. 4, after departing from Louisville Muhammad Ali International Airport in Kentucky. The McDonnell Douglas MD-11 was headed to Daniel K. Inouye International Airport in Honolulu. The FAA and NTSB will investigate. The NTSB will lead the investigati

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