LOUISVILLE, Ky. — A large UPS cargo plane with three people aboard crashed and exploded Tuesday while taking off from an airport in Louisville, Kentucky, igniting a massive fire that left a thick plume of black smoke over the area.

The plane crashed about 5:15 p.m. as it was departing for Honolulu from Louisville’s Muhammad Ali International Airport, the Federal Aviation Administration said.

Video showed flames on the plane’s left wing and a trail of smoke. The plane then lifted slightly off the ground before crashing and exploding in a huge fireball. Video also revealed portions of a building’s shredded roof next to the end of the runway.

“We know that there are injuries. We don’t know yet about fatalities, but we’re asking all Kentuckians to pray for those that have been impacted,” Ke

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