UPS Flight 2976 crashed at around 5.15pm local time on Tuesday as it was departing Louisville Muhammad Ali International Airport for Honolulu, Hawaii - and it burst into a fireball

At least three people have died after a cargo plane crashed and exploded during takeoff.

The UPS plane, which had 38,000 gallons of fuel (about 144,000 litres), erupted into a fireball moments after it left Louisville Muhammad Ali International Airport at 5.15pm yesterday (local time). Authorities confirmed the three fatalities, but this figure is expected to rise.

Louisville residents should remain indoors and shut doors and windows, amid what is "still a very dangerous situation". It is thought the pilot and crew on the UPS Flight 2976 died, however rescue operations continue for people trapped in build

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