Germany: Researchers have found in a new study that tailoring perioperative blood pressure targets based on preoperative nighttime mean arterial pressure (MAP) does not improve clinical outcomes in high-risk patients undergoing major abdominal surgery . The findings are from the IMPROVE-multi Randomized Clinical Trial, published in JAMA by Bernd Saugel and colleagues from the Department of Anesthesiology, University Medical Center Hamburg-Eppendorf, Germany. The trial investigated whether individualized MAP targets during surgery could reduce postoperative complications compared with routine blood pressure management. Intraoperative hypotension is known to contribute to organ injury, including kidney and heart damage. However, the potential benefit of customizing blood pressure

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