A UPS cargo plane with three crew members on board crashed shortly after take off Tuesday from Louisville International Airport in Kentucky, exploding into flames and sending a massive plume of black smoke over the area.

The US Federal Aviation Administration (FAA) said the McDonnell Douglas MD-11 departing for Hawaii crashed at around 5:15 p.m. local time (2215 GMT).

In a statement, UPS said three crew members were on board, adding “we have not confirmed any injuries/casualties.”

Louisville Mayor Craig Greenberg reported there were “multiple injuries” and that the plane was carrying a large amount of fuel.

The cause of the crash was under investigation by the FAA and the US National Transportation Safety Board (NTSB).

Video shared by local broadcaster WLKY appears to show the aircraf

See Full Page