Sarah Silverman started her stand up career in Boston. Not even out of high school, the New Hampshire comic took the stage for the first time at Stitches, the long-closed comedy club a stone’s throw from Boston University.

“My whole plan was, ‘I’m going to do an open mic.’ ” Silverman told the Herald. “I was 17, living in a dorm at BU for the summer (taking classes) and I got five minutes together and I went to Stitches.”

The five minutes went, well, OK.

“It was an open mic crowd so they were very nice,” Silverman said with a laugh. “And my high school history teacher came so I was very excited.”

The next Boston stage she’ll stand on will be very different.

On Saturday, Silverman joins host Denis Leary and guests including Conan O’Brien and Lenny Clarke for the 29th edition of Comics

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