Iowa State football continues its 2025 season on Saturday, Nov. 8, with a Big 12 Conference road game against TCU .

The Cyclones (5-4, 2-4 Big 12) have lost four straight games following a 5-0 start and are hoping to find some answers this week.

The Horned Frogs (6-2, 3-2) have won two straight contests, most recently 23-17 over West Virginia before enjoying a bye week last Saturday.

Here are some predictions and the betting lines for the game: Stream Iowa State vs. TCU for free on FUBO Expert MLB daily picks: Unique MLB betting insights only at USA TODAY

Iowa State vs. TCU odds, moneyline, over/under

Odds courtesy of BetMGM as of Friday evening.

Spread : Iowa State +7.5

Moneyline: Iowa State +235, TCU -290

Over/under : 57.5

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