A top-15 matchup highlights the Saturday college basketball schedule as Nate Oats and the No. 15 Alabama Crimson Tide take on Rick Pitino and the fifth-ranked St. John's Red Storm. St. John's opened its season with a 108-74 win over Quinnipiac, covering a 26.5-point spread. Alabama beat North Dakota 91-62 in its opener, but didn't cover the 36.5-point spread.

Tipoff from Madison Square Garden is set for noon ET. The Red Storm are 6.5-point favorites in the latest Alabama vs. St. John's odds, while the over/under is 171.5. Before making any St. John's vs. Alabama picks, check out the men's college basketball predictions and betting advice from the SportsLine Projection Model .

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