Welcome to the Wide Receiver Matchups to Target column for Week 10 of the 2025 NFL season. With nine games of data to work with, we can now lean on individual performance, matchup grades, pace of play, and implied totals to pinpoint the best WRs to target in daily fantasy lineups. Week 9 had its ups and downs. Puka Nacua , Amon-Ra St. Brown , and Wan'Dale Robinson approached 3x their salaries, while Rome Odunze and Ladd McConkey fell way short of expectations.

This week, we'll break down the top five WR/CB matchups using Pro Football Focus (PFF) grades, along with key usage metrics that indicate which players can realistically hit three times their DraftKings salary. This is meant to serve as a guide for both cash games and GPPs -- these guys are in position to smash regardless

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