The NFL Week 10 schedule features several division rivalries, including Bills vs. Dolphins, Seahawks vs. Cardinals and 49ers vs. Rams. The Bills have dominated the Dolphins in recent years, winning each of their last seven meetings against Miami, which includes a 31-21 win in Week 3. This time around, the Bills are favored by 9 points on the road, according to the latest Week 10 NFL odds . The Bills feature the NFL's top-ranked offense, averaging 385.5 yards per game, and SportsLine's model is backing Buffalo to record a convincing victory and cover the spread in 55% of simulations.

The model is also backing the Seahawks (-6.5) to cover the spread at home against the Cardinals, and Under 49.5 points to be scored in 49ers vs. Rams. Before locking in your Week 10 NFL picks, be sure to ch

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