A new study using Bayesian network analysis from the NESDA cohort suggests that depressive symptoms, especially those related to low energy, hypersomnia, and appetite or weight changes, are closely connected to diabetes, dyslipidemia, and systemic inflammation. These findings indicate a bidirectional relationship between depression and cardiometabolic disorders. Energy-related depressive symptoms were found to be particularly associated with waist circumference and diabetes, emphasizing the role of abdominal adiposity in linking mood disturbances to metabolic health. The study was published in the journal of Brain, Behavior, and Immunity by Arja O. and colleagues.

These data were from 1,059 participants with a lifetime diagnosis of depression, where 68% of the participants were female,

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