Construction has begun at the last parcel of land at the old Domino sugar site, marking the beginning of the end of a 12-year-long project.

A 545-high mixed-use building will soon rise at Domino Site B, sandwiched between 1 South First and the Domino Sugar Refinery on the Williamsburg waterfront. It will complete Two Trees’ redevelopment of the 11-acre site, which was first rezoned for development back in 2014.

The development, which does not yet have a snappy name like its neighbors at 325 Kent and 1 Domino Square, will include more than 1,200 units — 315 of which will be earmarked as affordable. An additional 105 affordable units will be constructed “offsite,” per zoning documents.

A rezoning of the already-rezoned lot was approved by the City Council late last month, after Two Trees

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