It’s only taken a few hundred years, but the “Spice Islands” region of eastern Indonesia — now known as the Maluku Islands — is once again attracting attention.

Virtually off-the-grid for global travelers just two decades ago, the archipelago and its hundreds of islands, along with several surrounding regions, are now on the bucket list of travelers craving new and unusual adventures at sea — all complemented by modern, high-end amenities.

Ranging from some of the most famous names in luxury hospitality to posh private yachts, there are more than a dozen options to explore the islands that sparked a 16th- and 17th-century “spice rush” for cloves, nutmeg and mace by Portuguese, Dutch and British traders, who could fetch high prices for their flavorsome commodities back in Europe. Most of

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