In September 2025, the US president claimed that paracetamol (acetaminophen) use during pregnancy caused autism. 1 A linked umbrella review by Sheikh and colleagues (doi:10.1136/bmj-2025-088141) 2 on paracetamol use during pregnancy and autism spectrum disorder and attention deficit/hyperactivity disorder (ADHD) arrives as a timely and corrective evidence synthesis in a topical area characterized by low quality data and the political elevation of flawed science. Central to the claims made by President Trump was a review by Prada and colleagues. 3 Reviews can be invaluable, particularly for readers who might find it challenging to navigate the vast literature on any given topic. As Sheikh and colleagues discuss, however, the review by Prada and colleagues as well as older reviews shou
Paracetamol (acetaminophen) use in pregnancy and risk of autism and ADHD
The BMJ11/21
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