Oregon Ducks players Jeremiah McClellan and Jamari Johnson celebrating a touchdown. Getty Images Gambling content 21+. The New York Post may receive an affiliate commission if you sign up through our links. Read our editorial standards for more information.

There is no doubt about which game is the headliner in Week 13.

“College GameDay” is in Eugene for USC at Oregon, and there’s no other game on the slate with higher stakes. The winner of this battle between former-Pac-12-now-Big-Ten rivals will be on its way to the College Football Playoff, while the loser will tumble out of contention.

The bookies clearly believe that this is Oregon’s game to lose, but USC has the ceiling to cause a ruckus as a 9.5-point underdog on Saturday afternoon.

USC vs. Oregon odds, prediction

Oregon’s

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