The final week of college football’s regular season is upon us, headlined by several blockbuster rivalry games that could help shape the College Football Playoff Field.

On this Thanksgiving holiday weekend, it starts with a large slate of games Friday, followed by several key games Saturday. Locally, the headliners is No. 6 Oregon at Washington. The Ducks need a win to lock up a CFP playoff berth. To the east is the weekend’s most significant game, Ohio State at Michigan.

Oregon State wraps up a forgettable 2025 season Saturday when it travels to Pullman to play Washington State.

Here are The Oregonian/OregonLive staff picks:

Season totals

Straight up

Sean Meagher : 126-44 (11-5 last week)

James Crepea : 124-46 (11-5)

Joel Odom: 123-47 (11-5)

Nick Daschel : 120-50 (13-3)

Ryan

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