(CNN) — Emerging from their holiday food comas and shuffling toward the nation’s airports and highways, some Americans may discover the biggest holiday indigestion has nothing to do with pie. A potent storm is muscling into the journey home, threatening to upend the post-turkey travel plans.

Some air passengers are already facing travel woes, with more than 1,600 US flights canceled as of Saturday, according to FlightAware, mostly due to winter weather in the Midwest.

A majority of the disruptions are in the Windy City, which is seeing steady snow. More than 1,000 flights coming into and out of Chicago’s O’Hare International Airport have been canceled and more than 700 have been delayed, according to FlightAware. The airport has seen about five inches of snow and flights into the airport

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