Key points

With or without caffeine, coffee is rich in biologically active substances that offer many health benefits.

However, for many coffee drinkers, decaffeinated coffee doesn’t taste as good as caffeinated coffee.

The decaffeination process decreases the concentration of water-soluble molecules that give coffee its flavor.

A pyrazine called 3-ethyl-2,5-dimethylpyrazine is the key determinant of the flavor and aroma of coffee.

Demand for decaffeinated beverages is growing worldwide due to negative perceptions of caffeine's effects on cardiovascular health. However, coffee has many well-known health benefits, which raises an important question: Does decaffeinated coffee offer the same health benefits as caffeinated coffee? The answer is a qualified yes. Fortunately, with or withou

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