The final game of the 2025 college football regular season is the college football game of the year: the No. 1 Ohio State Buckeyes vs. the No. 2 Indiana Hoosiers (12-0) in the Big Ten Championship Game on Saturday.

The conference title, the No. 1 seed in the College Football Playoff and possibly the Heisman Trophy will be on the line when these teams collide at Lucas Oil Stadium in Indianapolis. One year after winning the CFP national championship, the Buckeyes (12-0) have cruised through the regular season, playing only one game that was decided by fewer than 18 points. Freshman quarterback Julian Sayin leads the country in completion percentage (78.9) and passing efficiency (184.9).

Bet college football's championship week, including Ohio State vs. Indiana, at DraftKings Sports

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